Cancer BiologybioRxivPreprint
Carcinogen-induced preinvasive human squamous lung cancer is characterised by a novel atypical basal cell state and presents opportunities for chemoprevention
Wenrui Guo, Holly A. R. Giles, Alice Chernaik…·Frank M. McCaughan
This study develops a human model of early squamous lung cancer induced by a carcinogen, identifies a novel atypical basal cell state, and shows that capivasertib prevents and reverses the abnormal phenotype.
DOI 10.64898/2026.09.17.748423