Author

Allison F. Dennis

National Institutes of Health

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Genomics· 1

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Research Focus:benchmarking· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1 Organism:yeast· 1

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David J. ClarkiD· 1 shared Zhuwei XuiD· 1 shared

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David J. ClarkORCID

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Recent·Most cited

GenomicsNucleic Acids ResearchPeer-reviewedApr 4, 2024

Examining chromatin heterogeneity through PacBio long-read sequencing of M.EcoGII methylated genomes: an m6A detection efficiency and calling bias correcting pipeline

Allison F. Dennis, Zhuwei Xu, David J. Clark

The paper develops a pipeline to correct m6A detection biases in PacBio long-read sequencing of M.EcoGII-treated yeast nuclei, revealing chromatin heterogeneity at the single-molecule level.

11 citations

yeastlong-read sequencing

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