Author

Amanda J. McFarlane

Cancer Research UK Scotland Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Colin NixoniD· 2 shared Declan WhyteiD· 2 shared Frédéric FercoqiD· 2 shared Jim C. NormaniD· 2 shared John B. G. MackeyiD· 2 shared Karen BlythiD· 2 shared Leo M. CarliniD· 2 shared Robert WiesheuiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Colin NixonORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

Frédéric Fercoq, Gemma S. Cairns, Victoria Louise Bridgeman, Marco De Donatis, John B. G. Mackey, Alessia Floerchinger, Amanda J. McFarlane, Judith Secklehner, Ximena L. Raffo Iraolagoitia, Madeline Harrington, Lynn McGarry, Demi Brownlie, Declan Whyte, Lindsey W. G. Arnott, Colin Nixon, , Leo M. Carlin

This study shows that integrin conformation-dependent neutrophil slowing in pre-metastatic lungs obstructs capillaries and may contribute to immunosuppression in breast cancer.

Cell Reports · Mar 1, 2026Peer-reviewedImmunology

Uridine Phosphorylase-1 supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes of the lung

Declan Whyte, Sophie L Fisher, Christopher G J McKenzie, David P. Sumpton, Sandeep Dhayade, Emmanuel Dornier, Madeleine Moore, David Novo, Jasmine Peters, Robert Wiesheu, Michalis Gounis, Dale M. Watt, John B. G. Mackey, Amanda J. McFarlane, Frédéric Fercoq, , Cassie J. Clarke

EMBO Reports · Jul 23, 2025Peer-reviewedCancer Biology