Author

Robert Wiesheu

Cancer Research UK Scotland InstituteORCID 0000-0002-2079-4413Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Seth B. CoffeltiD· 4 shared Amanda J. McFarlane· 3 shared Colin NixoniD· 3 shared Declan WhyteiD· 3 shared Frédéric FercoqiD· 3 shared John B. G. MackeyiD· 3 shared Karen BlythiD· 3 shared Leo M. CarliniD· 3 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

Seth B. CoffeltORCID

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4 papers

Recent·Most cited

ImmunologyScience AdvancesPeer-reviewedMar 4, 2026

γδ T cells impair airway macrophage differentiation in lung adenocarcinoma

Ximena L. Raffo Iraolagoitia, Amanda J. McFarlane, Sarah Laing…·Leo M. Carlin

The paper identifies that CD27+ γδ T cells impair the differentiation of tumor-associated macrophages into airway macrophages in lung adenocarcinoma.

1 citation

mouseflow cytometry

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ImmunologyCell ReportsPeer-reviewedMar 1, 2026

Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

Frédéric Fercoq, Gemma S. Cairns, Victoria Louise Bridgeman…·Leo M. Carlin

This study shows that integrin conformation-dependent neutrophil slowing in pre-metastatic lungs obstructs capillaries and may contribute to immunosuppression in breast cancer.

6 citationstop 3%

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Cancer BiologyEMBO ReportsPeer-reviewedJul 23, 2025

Uridine Phosphorylase-1 supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes of the lung

Declan Whyte, Sophie L Fisher, Christopher G J McKenzie…·Cassie J. Clarke

15 citationstop 3%

mouseexperimental assay

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ImmunologyThe EMBO JournalPeer-reviewedMay 30, 2024

IL-27 maintains cytotoxic Ly6C+ gamma delta T cells that arise from immature precursors

Robert Wiesheu, Sarah C. Edwards, Ann Hedley…·Seth B. Coffelt

The paper identifies immature and mature subsets of IFNγ-producing γδ T cells, showing IL-27 supports cytotoxic function in mature cells but not immature ones.

13 citations

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