Lynn McGarry

This study identifies Podocalyxin as a regulator of glandular architecture in colorectal cancer, showing its role in promoting tumour growth and metastasis.

The paper identifies that CD27+ γδ T cells impair the differentiation of tumor-associated macrophages into airway macrophages in lung adenocarcinoma.

This study shows that integrin conformation-dependent neutrophil slowing in pre-metastatic lungs obstructs capillaries and may contribute to immunosuppression in breast cancer.

This study shows that radiotherapy promotes lung metastasis in PDAC by increasing MRCK activity, which can be inhibited by BDP9066.

This study shows that increased mRNA translation delays lung adenocarcinoma initiation and creates a vulnerability to MEK inhibitors in KRAS-driven tumors.

This study identifies a mechanism by which antisense oligonucleotides (ASOs) enter cells via scavenger receptors and EPHA2-mediated trafficking to reach nuclear-adjacent endosomes, enhancing their effectiveness.