Molecular BiologybioRxivPreprint
Regulated control of gene therapies with a drug induced switch
Alex Mas Monteys, Amiel A. Hundley, Paul T. Ranum…·Beverly L. Davidson
This paper introduces a drug-inducible switch system (Xon) for precise control of gene therapies, enabling gene silencing or replacement with oral small molecule inducers that are safe and bioavailable.
DOI 10.1101/2020.02.21.956664