Cancer BiologybioRxivPreprint
Impact of PI3K pathway alterations on response to immune checkpoint inhibitors in HPV-negative head and neck squamous cell carcinoma
Jong Chul Park, Nandini Pal Basak, Mateo Useche…·Srinivas Vinod Saladi
This study shows that PI3K pathway alterations in HPV-negative HNSCC are linked to poor outcomes and immune suppression, and that inhibiting PI3K can enhance immune response.
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