Author

Andreas J. Huber

Ludwig-Maximilians-Universität München

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

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Aida Cardona‐AlberichiD· 1 shared Christian BehrendsiD· 1 shared Francesco GubinelliiD· 1 shared Lena F. BurbullaiD· 1 shared Lena Jaschkowitz· 1 shared Leonie M. Heger· 1 shared Martina SchiffereriD· 1 shared Matteo RovereiD· 1 shared

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1 paper

Recent·Most cited

NeuroscienceScience AdvancesPeer-reviewedFeb 11, 2026

VMAT2 dysfunction impairs vesicular dopamine uptake, driving its oxidation and α-synuclein pathology in DJ-1-linked Parkinson's disease neurons

Leonie M. Heger, Francesco Gubinelli, Andreas J. Huber…·Lena F. Burbulla

This study shows that DJ-1 deficiency impairs VMAT2 function and vesicle dynamics, leading to dopamine oxidation and α-synuclein pathology in Parkinson's disease neurons.

7 citationstop 1%

humanproteomics

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