NeuroscienceNeurobiology of AgingPeer-reviewed
Tau in the brain interstitial fluid is fragmented and seeding-competent
Erica Barini, Gudrun Plotzky, Yulia Mordashova…·Kerstin Schlegel
This study identifies fragmented, phosphorylated Tau in brain interstitial fluid from Tau transgenic mice and shows that only a subset of these fragments can seed Tau aggregation in vitro.
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