Cell BiologybioRxivPreprint
ER Stress-Induced beta-Cell Apoptosis is Linked to Novel Select Lipid Signaling at the Transcriptional Level: Implications in T1D Development
XIAOYONG Y. LEI, Anil Kumar Challa, Susan E. Nozell…·Sasanka Ramanadham
This study identifies a novel lipid signaling pathway involving iPLA2β that links ER stress to β-cell apoptosis in T1D, revealing transcriptional regulation by iDLs and potential therapeutic targets.
DOI 10.64898/2026.03.02.708596