Author

Andrew S Krueger

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Systems Biology· 1

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:simulation· 1 Approach:statistical model· 1

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Christian Munck· 1 shared Gautam Dantas· 1 shared George M Church· 1 shared James Galagan· 1 shared Joseph Lehar· 1 shared Morten OA Sommer· 1 shared

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2015-2015 · peak 1/yr

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1 shared paperSystems Biology

Christian Munck

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1 paper

Recent·Most cited

Systems BiologybioRxivNov 6, 2015

Simulating serial-target antibacterial drug synergies using flux balance analysis

Andrew S Krueger, Christian Munck, Gautam Dantas…·Morten OA Sommer

This study extends flux balance analysis to simulate drug synergies by modeling chemical inhibitors as flux diversion, showing it can predict serial target synergies in E. coli.

DOI 10.1371/journal.pone.0147651

E. colistatistical model

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