GeneticsbioRxivPreprint
Loss-of-function of ALDH3B2 transdifferentiates human pancreatic duct cells into beta-like cells
Jian Li, Kevin Bode, Yu‐Chi Lee…·Yi Peng
This study shows that knocking out ALDH3B2 in human pancreatic duct cells converts them into beta-like cells that function and reduce blood glucose in mice.
DOI 10.1101/2024.05.13.593941