Synthetic BiologyACS Synthetic BiologyPeer-reviewed
Genetically encoded SpyTag enables modular AAV retargeting via SpyCatcher-fused ligands for targeted gene delivery.
Anja Armbruster, Maximilian Hörner, Hanna J. Wagner…·Wilfried Weber
This paper introduces a modular AAV retargeting platform using SpyTag/SpyCatcher for targeted gene delivery, demonstrating specific cancer cell transduction and therapeutic potential.