Author

Anju Kombara

Boehringer Ingelheim (Austria)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Assay:CRISPR screen· 1 Organism:human· 1

Frequent Co-Authors

Aileen B. FrostiD· 1 shared Alessio CiulliiD· 1 shared Alexandra PopaiD· 1 shared Andrea Stingu· 1 shared Andrew S. BoghossianiD· 1 shared Barbara MairiD· 1 shared Ceren Bilgilier· 1 shared Christiane C. KofinkiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Aileen B. FrostORCID

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2 papers

Recent·Most cited

Cancer BiologyACS Chemical BiologyPeer-reviewedJul 3, 2024

Confounding factors in targeted degradation of short-lived proteins

Vesna Vetma, Laura Casares Perez, Ján Eliaš…·Manfred Koegl

This study shows that the natural half-life of a target protein significantly affects degradation by degrader agents and highlights confounding factors in screening for protein degraders.

53 citationstop 2%

statistical modeldrug response / drug discovery

𝕏 PostBluesky

BioinformaticsCell ReportsPeer-reviewedApr 30, 2024

Genetic dependencies associated with transcription factor activities in human cancer cell lines

Venu Thatikonda, Verena Supper, Johannes Wachter…·Alexandra Popa

The paper identifies genetic vulnerabilities linked to transcription factor activities in cancer cell lines using CRISPR knockout data and validates targets associated with TEAD1.

3 citations

humanCRISPR screen

𝕏 PostBluesky