BiochemistryNature Structural & Molecular BiologyPeer-reviewed
Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by minor groove anchor competition
Wataru Kobayashi, Anna Sappler, Daniel Bollschweiler…·Kiku-e K. Tachibana
The paper determines the structure of NR5A2 bound to a nucleosome, revealing how it competes with the minor groove anchor to destabilize nucleosomes and facilitate gene expression during reprogramming.
26 citations