Systems BiologyPLoS Computational BiologyPeer-reviewed
Data-driven model reveals increased stability of CAG-expanded huntingtin RNA due to MID1 binding
Yuhong Liu, Annika Reisbitzer, Domagoj Dorešić…·Tatjana Tchumatchenko
The paper develops a computational model to show that MID1 binding increases mutant huntingtin RNA stability, validated experimentally.
DOI 10.1371/journal.pcbi.1014342