Cell BiologybioRxivPreprint
Constitutive Androstane Receptor induces Ribonucleotide Reductase-M2 expression and maintains hepatocyte ploidy in mice
Anjana Asokakumar, Bhoomika Mathur, Sandip Chorghade…·Sayeepriyadarshini Anakk
This study shows that CAR maintains hepatocyte ploidy by inducing RRM2 expression, which supports DNA synthesis and tetraploid hepatocyte formation in mice.
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