BioengineeringbioRxivPreprint
The T-cell niche tunes immune function through modulation of the cytoskeleton and TCR-antigen forces
Anna V. Kellner, Rae Hunter, Priscilla Do…·Khalid Salaita
This study shows that the adipocyte niche impairs T-cell function by modulating cytoskeletal dynamics and reducing TCR-antigen forces in both mice and human T-cells.
DOI 10.1101/2024.01.31.578101