Author

Anthony Jenks

University of Minnesota

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Amir ShimoniD· 1 shared Céline BergonziiD· 1 shared David DaudéiD· 1 shared Éric ChabrièreiD· 1 shared Mikael H. EliasiD· 1 shared Nathan Hoekstra· 1 shared Pauline Jacquet· 1 shared Raphaël BillotiD· 1 shared

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1 shared paperBiochemistry

Amir ShimonORCID

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Recent·Most cited

BiochemistryJACS AuPeer-reviewedApr 25, 2024

Changes in Active Site Loop Conformation Relate to the Transition toward a Novel Enzymatic Activity

Pauline Jacquet, Raphaël Billot, Amir Shimon…·Mikael H. Elias

The paper redesigns the active site of lactonase SsoPox to enhance phosphotriester catalytic activity, revealing that loop conformation changes are critical for activity shifts.

15 citations

protein structureexperimental assay

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