NeuroscienceNature CommunicationsPeer-reviewed
Xenotransplantation of Human PSC-derived Microglia Creates a Chimeric Mouse Brain Model that Recapitulates Features of Adult Human Microglia
Ranjie Xu, Xiaoxi Li, Andrew J. Boreland…·Peng Jiang
This study xenotransplants human PSC-derived microglia into mice to create a chimeric brain model that retains human microglial identity and exhibits disease-relevant responses.
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