BiochemistrybioRxivPreprint
AMPK-dependent FLCN phosphorylation activates a survival response to hypoxia
Josué M. J. Ramírez-Reyes, Ariadna Pollato-Blanco, Stéphanie Duhamel…·Arnim Pause
The paper identifies an AMPK-FLCN-TFE3 pathway that promotes hypoxia survival through lysosomal and mitochondrial biogenesis, with implications for cancer therapy.
DOI 10.64898/2026.05.20.726614