Author

Ariel Fromowitz

Department of Oncology, Blood Cancer Institute, Montefiore Einstein Comprehensive Cancer Center, Bronx, NY 10461, USA.

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

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Aishwarya Kulkarni· 1 shared Amit VermaiD· 1 shared Daniel T. StarczynowskiiD· 1 shared David ShechteriD· 1 shared Davy Lee· 1 shared Diane HeiseriD· 1 shared Elizabeth Tseng· 1 shared H. Leighton GrimesiD· 1 shared

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Aishwarya Kulkarni

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1 paper

Recent·Most cited

Cancer BiologybioRxivFeb 4, 2024

Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation

Meenakshi Venkatasubramanian, Leya Schwartz, Nandini Ramachandra…·Nathan Salomonis

The paper identifies a splicing mechanism in AML independent of mutations, showing it drives poor prognosis and can be targeted with PRMT5 inhibition.

DOI 10.1126/scitranslmed.adr1471

humanbulk RNA-seq

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