GeneticsDevelopmental CellPeer-reviewed
Sex-specific regulation of metabolic health and vertebrate lifespan by AMP biosynthesis
Gwendoline Astre, Tehila Atlan, Uri Goshtchevsky…·Itamar Harel
This study shows that mutating APRT in turquoise killifish extends male lifespan and improves metabolic health, with mitochondrial function and AMPK activity playing key roles.
43 citations