BiochemistrybioRxivPreprint
Interactions between Viperin, IRAK1 and TRAF6 couple innate immune signaling to antiviral ribonucleotide synthesis
Arti B. Dumbrepatil, Soumi Ghosh, Ayesha M. Patel…·E. Neil. G Marsh
This study shows that Viperin, IRAK1, and TRAF6 interact to link innate immune signaling with antiviral ddhCTP synthesis through ubiquitination and enzymatic activation.
DOI 10.1101/318840