Molecular BiologyCell ReportsPeer-reviewed
Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1
Joseph S. Bowness, Tatyana B. Nesterova, Guifeng Wei…·Neil Brockdorff
The paper shows SPEN and Polycomb work together in parallel for Xist-mediated gene silencing, and SmcHD1 recruitment is needed for silencing X-linked genes during differentiation.
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