Molecular BiologybioRxivPreprint
SNPD-siKRAS: siRNA specifically inhibits KRAS with a single-nucleotide mutation
Yoshiaki Kobayashi, Yoshimasa Asano, Atsushi Sato…·Kumiko Ui-Tei
This paper develops SNPD-siKRAS, a siRNA that specifically targets mutated KRAS without affecting wild-type KRAS, showing efficacy in cell cultures and xenograft models.
DOI 10.1101/2025.09.18.677211