Author

Austin Witt

Virginia Commonwealth University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Claire D. JamesiD· 3 shared Apurva Tadimari PrabhakariD· 2 shared Aya H. Youssef· 2 shared Iain M. MorganiD· 2 shared Jenny D Roe· 2 shared Molly L. BristoliD· 2 shared Xu Wang· 2 shared Andrew Day· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMolecular Biology

Claire D. JamesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Regulation and Function of the HPV16 CircE7 RNA

Eunice E. Lee, Yihui Huang, Eleanor M. Dowell, Kaitlyn Walsh, Calvin Hosler, Austin Witt, Odera Ifeacho, Doreen N. Palsgrove, Andrew Day, Claire D. James, Richard C. Wang

This study investigates the regulation and function of HPV16 circE7 RNA, showing that m6A modification and IRES-like motifs are critical for its formation and translation, impacting viral replication and transformation.

Journal of Virology · Sep 17, 2026Peer-reviewedMolecular Biology

HPV16 recruitment of SMARCAL1 to viral and host replication forks is required for the viral life cycle

Claire D. James, Aya H. Youssef, Jenny D Roe, Floriana Cappiello, Francesca Antonella Aiello, Benedetta Perdichizzi, Rachel L. Lewis, Austin Witt, Apurva Tadimari Prabhakar, Xu Wang, Molly L. Bristol, Pietro Pichierri, Iain M. Morgan

This paper shows that HPV16 requires SMARCAL1 to recruit to viral and host replication forks, which is essential for its life cycle and prevents DNA damage and genome integration.

mBio · Mar 30, 2026Peer-reviewedMicrobiology

Differentiation-Dependent Proximity Proteomics Identifies Novel Host Factors Linked to HPV16 E2 Function

Claire D. James, Aya H. Youssef, Apurva Tadimari Prabhakar, Jenny D Roe, Elinor Lu, Austin Witt, Sarita Giri, Molly L. Bristol, Phoebe V. Bridy, Xu Wang, Arjun Rijal, Charles E. Lyons, Iain M. Morgan

This study identifies novel host factors interacting with HPV16 E2 during differentiation using proximity proteomics, revealing a cooperative E2-TOPBP1-NCL axis critical for viral genome stability.

mBio · Jan 12, 2026Peer-reviewedCancer Biology