NeurosciencebioRxivPreprint
An isogenic panel of single App knock-in mouse models of Alzheimer's disease confers differential profiles of β-secretase inhibition and endosomal abnormalities
Naoto Watamura, Kaori Sato, Gen Shiihashi…·Hiroki Sasaguri
This study develops App knock-in mice without Swedish mutations to investigate β-secretase inhibition and endosomal abnormalities in Alzheimer's disease.
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