Cancer BiologyACS Chemical BiologyPeer-reviewed
Obtusaquinone is a cysteine modifying compound that targets Keap1 for degradation
c. E. badr, C. C. da Hora, A. Kirov…·B. A. Tannous
This study identifies Obtusaquinone as a cysteine-modifying compound that targets Keap1 for degradation, activating the Nrf2 pathway through proteasomal degradation.
DOI 10.1021/acschembio.0c00104