Author

B. Ambrose

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:fluorescence / live-cell microscopy· 2 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1 Research Focus:software / tool· 1

Frequent Co-Authors

T. D. Craggs· 3 shared A. Barth· 1 shared A. Cadby· 1 shared A. Hartmann· 1 shared A. J. Cadby· 1 shared A. Kapanidis· 1 shared A. Sefer· 1 shared B. C. Bateman· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiophysics

T. D. Craggs

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3 papers

Recent·Most cited

Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins

G. Agam, C. Gebhardt, M. Popara, R. Maechtel, J. Folz, B. Ambrose, N. Chamachi, S. Y. Chung, T. D. Craggs, M. de Boer, D. Grohmann, T. Ha, A. Hartmann, J. Hendrix, V. Hirschfeld, , T. Cordes

This study evaluates the reliability and accuracy of single-molecule FRET for measuring protein structural dynamics and distances, finding high precision and accuracy with specific uncertainty limits.

bioRxiv · Aug 3, 2022Biophysics

An Open-source, Cost-efficient Excitation Module for Single-molecule Microscopy

D. R. George, B. Ambrose, A. J. Cadby, T. D. Craggs

The paper introduces an open-source, cost-efficient excitation module for single-molecule spectroscopy, demonstrating its suitability for various techniques and reducing instrument costs by ~50%.

bioRxiv · Feb 28, 2022 · PreprintBiophysics

The smfBox: an open-source platform for single-molecule FRET

B. Ambrose, J. Baxter, J. Cully, M. Willmott, E. Steele, B. C. Bateman, M. L. Martin-Fernandez, A. Cadby, J. Shewring, M. Aaldering, T. D. Craggs

The paper introduces smfBox, an open-source confocal smFRET platform that reduces costs and provides detailed instructions and software to make smFRET accessible to non-specialists.

Nature Communications · Nov 6, 2020Peer-reviewedBiophysics