Author

A. Sefer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:structural biology· 1

Frequent Co-Authors

J. Michaelis· 2 shared A. Barth· 1 shared A. Hartmann· 1 shared A. Kapanidis· 1 shared B. Ambrose· 1 shared C. A. M. Seidel· 1 shared C. G. Huebner· 1 shared C. Gebhardt· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiophysics

J. Michaelis

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Author profile →

2 papers

Recent·Most cited

Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins

G. Agam, C. Gebhardt, M. Popara, R. Maechtel, J. Folz, B. Ambrose, N. Chamachi, S. Y. Chung, T. D. Craggs, M. de Boer, D. Grohmann, T. Ha, A. Hartmann, J. Hendrix, V. Hirschfeld, , T. Cordes

This study evaluates the reliability and accuracy of single-molecule FRET for measuring protein structural dynamics and distances, finding high precision and accuracy with specific uncertainty limits.

bioRxiv · Aug 3, 2022Biophysics

Structural dynamics of DNA strand break sensing by PARP-1 at a single-molecule level

A. Sefer, E. Kallis, T. Eilert, C. Roecker, D. Neuhaus, S. Eustermann, J. Michaelis

This study investigates how PARP-1 senses DNA single-strand breaks at the single-molecule level, revealing an induced fit mechanism involving multi-domain assembly and inhibitor effects.

bioRxiv · Feb 26, 2022Biophysics