Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
A. Luginina, I. Maslov, P. Khorn, O. Volkov, A. Khnykin, P. Kuzmichev, M. Shevtsov, A. Belousov, D. Dashevskii, D. Kornilov, E. Bestsennaia, J. Hofkens, J. Hendrix, T. Gensch, V. Cherezov, , V. I. Borshchevskiy
The paper compares GPCR expression in the LEXSY eukaryotic system to insect cells, finding higher protein yield in LEXSY for the A2A adenosine receptor.
Journal of Molecular Biology · Dec 1, 2023Peer-reviewedBiophysics
A. Belousov, I. Maslov, P. Orekhov, P. Khorn, P. Kuzmichev, N. Baleeva, V. Motov, A. Bogorodskiy, S. Krasnova, K. Mineev, D. Zinchenko, E. Zernii, V. Ivanovich, S. Permyakov, J. Hofkens, , V. Borshchevskiy
This study develops GFP-inspired dyes to monitor ligand-induced conformational changes in GPCRs, showing fluorescence responses to agonists and allosteric modulators.
bioRxiv · Jun 1, 2023Biophysics
Q. Coucke, N. Parveen, G. S. Fernandez, C. Qian, J. Hofkens, Z. Debyser, J. Hendrix
The paper introduces particle-based phasor-FLIM-FRET to quantify protein-protein interactions in single viral particles, showing it can accurately measure FRET efficiency with low signal intensities.
bioRxiv · May 31, 2023Biophysics
G. Agam, C. Gebhardt, M. Popara, R. Maechtel, J. Folz, B. Ambrose, N. Chamachi, S. Y. Chung, T. D. Craggs, M. de Boer, D. Grohmann, T. Ha, A. Hartmann, J. Hendrix, V. Hirschfeld, , T. Cordes
This study evaluates the reliability and accuracy of single-molecule FRET for measuring protein structural dynamics and distances, finding high precision and accuracy with specific uncertainty limits.
bioRxiv · Aug 3, 2022Biophysics
V. Lemmens, B. Thevelein, S. Kankowski, H. Mizuno, J. Meier, S. Rocha, B. Brone, J. Hendrix
This study functionally characterizes GlyR-3 splice variant heteropentamerization using fluorescence microscopy and electrophysiology, showing they adopt the mobility of the K variant and exhibit conductance similar to 3K.
bioRxiv · Feb 18, 2021Biochemistry
I. Maslov, O. Volkov, P. Khorn, P. Orekhov, A. Gusach, P. Kuzmichev, A. Gerasimov, A. Luginina, Q. Coucke, A. Bogorodskiy, V. Gordeliy, S. Wanninger, A. Barth, J. Hofkens, V. Cherezov, , V. Borshchevskiy
This study uses smFRET to analyze the conformational dynamics of the A2A adenosine receptor, revealing slow and fast dynamics in different ligand-bound states.
bioRxiv · Nov 26, 2020Biophysics
A. Roth, C. Martens, T. van Oene, A. Barth, S. Wanninger, D. C. Lamb, J. Hendrix, C. Govaerts
This study uses smFRET to show substrate binding modulates conformational kinetics of LmrP, revealing substrate-dependent structural changes in MFS transporters.
bioRxiv · Apr 9, 2020 · PreprintBiophysics
R. B. Davidson, J. Hendrix, B. J. Geiss, M. McCullagh
This study investigates the RNA-dependent structural dynamics of the flavivirus NS3 helicase RNA-binding loop using molecular dynamics simulations, revealing how RNA binding stabilizes specific conformations and impacts NTPase activity.
bioRxiv · Jan 15, 2020Biophysics
A. Barth, J. Hendrix, D. Fried, Y. Barak, E. Bayer, D. C. Lamb
This study uses single-molecule techniques and simulations to show that cohesin-cohesin interactions and linker flexibility in scaffoldin proteins are critical for cellulosome structure and function.
bioRxiv · May 22, 2018Biophysics