Author

B. Asquith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:variant calling· 1

Frequent Co-Authors

C. Kaur· 2 shared A. Yan· 1 shared B. J. Debebe· 1 shared C. Bangham· 1 shared C. N. Kibirige· 1 shared C. Niederalt· 1 shared D. C. Macallan· 1 shared D. J. Laydon· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

C. Kaur

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes

L. Mora-Bitria, B. J. Debebe, K. Miners, K. Ladell, C. Kaur, J. A. Traherne, W. Jiang, L. Hadcocks, N. A. R. McQuibban, J. Trowsdale, F. S. Wong, N. Pontikos, C. Niederalt, B. Asquith

The paper investigates how inhibitory KIRs modify HLA class II protective associations in Type 1 Diabetes, finding that iKIRs reduce HLA class II-mediated protection.

bioRxiv · Mar 27, 2024 · PreprintImmunology

Absolute quantification of rare gene targets in limited samples using crude lysate and ddPCR

C. Kaur, S. Adams, C. N. Kibirige, B. Asquith

This paper develops and validates a crude lysate ddPCR assay for accurate absolute quantification of rare genes like TRECs from limited clinical samples, eliminating DNA extraction and improving performance over standard ddPCR.

bioRxiv · Mar 27, 2024Biochemistry

The Impact of Model Assumptions in Interpreting Cell Kinetic Studies

A. Yan, I. Sadreev, J. Mackerodt, Y. Zhang, D. C. Macallan, R. Busch, B. Asquith

The paper examines how three common assumptions in stable isotope labelling studies affect interpretations of cell dynamics and proposes ways to reduce resulting errors.

bioRxiv · Mar 17, 2024Immunology

The relative contributions of infectious and mitotic spread to HTLV-1 persistence

D. J. Laydon, V. Sunkara, L. Boelen, C. Bangham, B. Asquith

This paper estimates the ratio of infectious to mitotic spread of HTLV-1 during chronic infection and finds that infectious spread persists at low levels after proviral load reaches set point.

bioRxiv · Oct 9, 2019Immunology