Lymphoid follicle formation and human vaccination responses recapitulated in an organ-on-a-chip
G. Goyal, P. Prabhala, G. Mahajan, B. Bausk, T. Gilboa, L. Xie, Y. Zhai, R. Lazarovits, A. Mansour, M. S. Kim, D. Curran, J. Long, S. Sharma, L. Cohen, O. Levy, , D. E. Ingber
This paper demonstrates the formation of lymphoid follicles in a human organ-on-a-chip model and shows improved vaccine responses compared to 2D cultures.
bioRxiv · Apr 28, 2021 · PreprintImmunology