Interferon-α subtype treatment induces the repression of SRSF1 in HIV-1 target cells and affects HIV-1 post integration steps
H. Sertznig, F. Roesmann, B. Bleekmann, C. Elsner, M. L. Santiago, J. Schuhenn, Y. Benatzy, R. Snodgrass, S. Esser, K. Sutter, U. Dittmer, M. Widera
This study shows that IFN-α treatment represses SRSF1 in HIV-1 target cells, affecting post-integration viral replication steps by altering splicing and transcription.
bioRxiv · Jun 11, 2021 · PreprintMicrobiology