M. L. Santiago

This study shows hnRNPA0 limits HIV-1 replication by inhibiting LTR activity and ribosomal frameshifting, with lower expression in HIV-infected individuals.

This study shows that IFN-α treatment represses SRSF1 in HIV-1 target cells, affecting post-integration viral replication steps by altering splicing and transcription.

This study shows that T cell depletion in rhesus macaques does not cause severe SARS-CoV-2 disease but delays viral clearance, and T cells are not essential for immunological memory or protection against re-infection.

This study shows emerging SARS-CoV-2 variants are more resistant to human interferons, suggesting innate immune evasion plays a key role in their evolution.

This study investigates whether HIV infection alters IFNAR2 expression on mucosal immune cells and finds no significant changes in IFNAR2 expression in HIV+ patients or after HIV-1 infection ex vivo.