Author

K. Sutter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Organism:human· 8 Research Focus:host-pathogen & immune response· 6 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:flow cytometry· 2

Frequent Co-Authors

U. Dittmer· 7 shared M. Trilling· 4 shared C. Elsner· 3 shared J. Liu· 3 shared J. Schuhenn· 3 shared M. L. Santiago· 3 shared M. Lu· 3 shared M. Widera· 3 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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7 shared papersImmunology

U. Dittmer

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Targeted mutations in IFNα2 improve its antiviral activity against various viruses

Z. Karakoese, V. T. K. Le-Trilling, J. Schuhenn, S. Francois, M. Lu, J. Liu, M. Trilling, D. Hoffmann, U. Dittmer, K. Sutter

The paper identifies critical antiviral residues in IFN subtypes and designs improved IFN molecules with enhanced antiviral activity against HIV and HBV.

bioRxiv · Sep 6, 2023Immunology

Cellular hnRNPA0 limits HIV-1 production by interference with LTR-activity and programmed ribosomal frame-shifting

F. Roesmann, H. Sertznig, K. Klaassen, A. Wilhelm, D. Heininger, C. Elsner, M. L. Santiago, S. Esser, K. Sutter, U. Dittmer, M. Widera

This study shows hnRNPA0 limits HIV-1 replication by inhibiting LTR activity and ribosomal frameshifting, with lower expression in HIV-infected individuals.

bioRxiv · Aug 8, 2023 · PreprintMicrobiology

Interferon-α subtype treatment induces the repression of SRSF1 in HIV-1 target cells and affects HIV-1 post integration steps

H. Sertznig, F. Roesmann, B. Bleekmann, C. Elsner, M. L. Santiago, J. Schuhenn, Y. Benatzy, R. Snodgrass, S. Esser, K. Sutter, U. Dittmer, M. Widera

This study shows that IFN-α treatment represses SRSF1 in HIV-1 target cells, affecting post-integration viral replication steps by altering splicing and transcription.

bioRxiv · Jun 11, 2021 · PreprintMicrobiology

Differential interferon-α subtype immune signatures suppress SARS-CoV-2 infection

J. Schuhenn, T. L. Meister, D. Todt, T. Bracht, K. Schork, J.-N. Billaud, C. Elsner, N. Heinen, Z. Karakoese, S. Haid, S. Kumar, L. Brunotte, M. Eisenacher, J. Chen, Z. Yuan, , S. Pfaender

The paper identifies differential antiviral effects of IFN-alpha subtypes against SARS-CoV-2 and highlights IFN5's superior activity, suggesting therapeutic potential.

bioRxiv · May 20, 2021 · PreprintCell Biology

SARS-CoV-2-specific T cell memory is long-lasting in the majority of convalsecent COVID-19 individuals

Z. Li, J. Liu, H. Deng, X. Yang, H. Wang, X. Feng, G. Zelinskyy, M. Trilling, K. Sutter, M. Lu, B. Wang, D. Yang, X. Zheng, J. Liu

This study shows that SARS-CoV-2-specific T cell memory persists for at least 9 months in most convalescent COVID-19 individuals, with some responses lasting longer.

bioRxiv · Nov 15, 2020 · PreprintMicrobiology

Impaired cytotoxic CD8+ T cell response in elderly COVID-19 patients

J. Westmeier, K. Paniskaki, Z. Karaköse, T. Werner, K. Sutter, S. Dolff, M. Overbeck, A. Limmer, J. Liu, X. Zheng, T. Brenner, M. M. Berger, O. Witzke, M. Trilling, M. Lu, , G. Zelinskyy

This study examines CD8+ T cell cytotoxicity in mild COVID-19 patients, finding reduced cytotoxic potential in elderly individuals over 80 years old.

bioRxiv · Aug 21, 2020Immunology

Type I interferons sensitise HIV-1-reactivating T-cells for NK cell-mediated elimination despite HDACi-imposed dysregulation of innate immunity

J. Prigann, D. Postmus, A. J. Pietrobon, E. Wyler, J. Jansen, L. Moeller, J. Fadejeva, T. Steijaert, C. Fischer, U. Koppe, B. Gunsenheimer-Bartmeyer, K. Meixenberger, S. Vitcetz, M. Sohn, L. Loyal, , C. GOFFINET

This study shows that type I interferons can enhance NK cell killing of HIV-1-reactivating T-cells despite HDACi-induced immune dysregulation, suggesting a potential strategy to improve shock-and-kill approaches.

bioRxiv · May 4, 2020 · PreprintMicrobiology

HIV infection does not alter Interferon α/β receptor expression on mucosal immune cells

J. Ickler, S. Francois, M. Widera, M. L. Santiago, U. Dittmer, K. Sutter

This study investigates whether HIV infection alters IFNAR2 expression on mucosal immune cells and finds no significant changes in IFNAR2 expression in HIV+ patients or after HIV-1 infection ex vivo.

bioRxiv · Jul 2, 2019Immunology