Author

C. Elsner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:human· 4 Assay:bulk RNA-seq· 3 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

U. Dittmer· 4 shared K. Sutter· 3 shared D. Todt· 2 shared E. Steinmann· 2 shared F. Roesmann· 2 shared H. Sertznig· 2 shared J. Schuhenn· 2 shared M. L. Santiago· 2 shared

Activity by Year

2021-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

U. Dittmer

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Cellular hnRNPA0 limits HIV-1 production by interference with LTR-activity and programmed ribosomal frame-shifting

F. Roesmann, H. Sertznig, K. Klaassen, A. Wilhelm, D. Heininger, C. Elsner, M. L. Santiago, S. Esser, K. Sutter, U. Dittmer, M. Widera

This study shows hnRNPA0 limits HIV-1 replication by inhibiting LTR activity and ribosomal frameshifting, with lower expression in HIV-infected individuals.

bioRxiv · Aug 8, 2023 · PreprintMicrobiology

A base-line cellular antiviral state is maintained by cGAS and its most frequent naturally occurring variant rs610913

J. Kazmierski, C. Elsner, K. Doehner, S. Xu, A. Ducroux, F. Pott, J. Jansen, C. W. Thorball, O. Zeymer, X. Zhou, R. Fedorov, J. Fellay, M. W. Loeffler, A. N. R. Weber, B. Sodeik, C. Goffinet

This study shows that the cGAS variant rs610913 maintains a baseline antiviral state, slightly altering susceptibility to viral infections without gross phenotypic differences.

bioRxiv · Aug 24, 2021 · PreprintImmunology

Size Matters: A Mechanistic Model of Nanoparticle Curvature Effects on Amyloid Fibril Formation

T. John, J. Adler, C. Elsner, J. Petzold, M. Krueger, L. L. Martin, D. Huster, H. J. Risselada, B. Abel

This study investigates how nanoparticle curvature affects amyloid fibril formation of different peptides, finding that smaller nanoparticles inhibit while larger ones accelerate aggregation.

bioRxiv · Jul 1, 2021Biochemistry

Interferon-α subtype treatment induces the repression of SRSF1 in HIV-1 target cells and affects HIV-1 post integration steps

H. Sertznig, F. Roesmann, B. Bleekmann, C. Elsner, M. L. Santiago, J. Schuhenn, Y. Benatzy, R. Snodgrass, S. Esser, K. Sutter, U. Dittmer, M. Widera

This study shows that IFN-α treatment represses SRSF1 in HIV-1 target cells, affecting post-integration viral replication steps by altering splicing and transcription.

bioRxiv · Jun 11, 2021 · PreprintMicrobiology

Differential interferon-α subtype immune signatures suppress SARS-CoV-2 infection

J. Schuhenn, T. L. Meister, D. Todt, T. Bracht, K. Schork, J.-N. Billaud, C. Elsner, N. Heinen, Z. Karakoese, S. Haid, S. Kumar, L. Brunotte, M. Eisenacher, J. Chen, Z. Yuan, , S. Pfaender

The paper identifies differential antiviral effects of IFN-alpha subtypes against SARS-CoV-2 and highlights IFN5's superior activity, suggesting therapeutic potential.

bioRxiv · May 20, 2021 · PreprintCell Biology

Comparable environmental stability and disinfection profiles of the currently circulating SARS-CoV-2 variants of concern B.1.1.7 and B.1.351

T. L. Meister, J. Fortmann, D. Todt, N. Heinen, A. Ludwig, Y. Brueggemann, C. Elsner, U. Dittmer, S. Pfaender, E. Steinmann

This study compares the environmental stability and disinfection profiles of SARS-CoV-2 variants B.1.1.7 and B.1.351 to the wildtype, finding comparable susceptibility to disinfection and surface stability.

bioRxiv · Apr 7, 2021Microbiology