ImmunologybioRxiv
Sustained liver HBsAg loss and clonal T and B cell expansion upon therapeutic DNA vaccination require low HBsAg levels
N. Conceicao-Neto, W. Pierson, M. Vacca…·E. Van Gulck
This study shows that sustained HBsAg loss and immune cell expansion in the liver occur after therapeutic DNA vaccination in a mouse model when HBsAg levels are low.