BiophysicsbioRxiv
Stability Criterion for the Assembly of Hybrid Lipid-Polymer-Nucleic Acid Nanoparticles
J. L. Paris, R. Gaspar, F. Coelho…·B. F. B. Silva
The paper demonstrates that a polycation-DNA core and oppositely charged liposome shell are necessary for stable LPNP formation, with a critical ratio of liposome to polyplex number ensuring stability.
DOI 10.1021/acsnano.3c07204