Author

B. Gruning

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Organism:virus· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. De Klerk· 1 shared A. G. Lucaci· 1 shared A. J. Greaney· 1 shared A. Nekrutenko· 1 shared A. Sigal· 1 shared A. von Gottberg· 1 shared B. Murrell· 1 shared B. T. Sewell· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperEvolutionary Biology

A. De Klerk

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1 paper

Recent·Most cited

Selection analysis identifies unusual clustered mutational changes in Omicron lineage BA.1 that likely impact Spike function

D. P. Martin, S. Lytras, A. G. Lucaci, W. Maier, B. Gruning, S. D. Shank, S. Weaver, O. S. MacLean, R. J. Orton, P. Lemey, M. F. Boni, H. Tegally, G. W. Harkins, C. Scheepers, J. N. Bhiman, , S. L. Kosakovsky Pond

The paper identifies 13 rare mutations in the Omicron S-gene that cluster in functionally important regions and likely impact Spike function, suggesting cooperative interactions that mitigate fitness costs.

bioRxiv · Jan 14, 2022 · PreprintEvolutionary Biology