Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
B. Hamza, A. B. Miller, L. Meier, M. Stockslager, E. M. King, S. R. Ng, K. L. DeGouveia, N. Mulugeta, N. L. Calistri, H. Strouf, L. Lin, C. R. Chin, R. Weinberg, A. K. Shalek, T. Jacks, S. Manalis
This study measures CTC kinetics and metastatic potential by exchanging blood between tumor-bearing and healthy mice, finding short CTC half-life and high shedding rates.
bioRxiv · Nov 1, 2020Cancer Biology