Author

E. M. King

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. B. Miller· 1 shared A. K. Shalek· 1 shared B. Hamza· 1 shared B. P. Kleinstiver· 1 shared C. J. Tou· 1 shared C. R. Chin· 1 shared D. Rufino-Ramos· 1 shared H. Strouf· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. B. Miller

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Author profile →

4 papers

Recent·Most cited

Click editing enables programmable genome writing using DNA polymerases and HUH endonucleases

J. F. da Silva, C. J. Tou, E. M. King, M. L. Eller, L. Ma, D. Rufino-Ramos, B. P. Kleinstiver

This paper introduces click editing, a genome writing platform that enables precise installation of genetic edits using DNA polymerases and HUH endonucleases, with minimal indels and no unwanted insertions.

bioRxiv · Sep 12, 2023 · PreprintBioengineering

Peptides Mimicking RS Repeats Modulate Phase Separation of SRSF1, Revealing a Reliance on Combined Stacking and Electrostatic Interactions

T. E. Fargason, N. I. U. De Silva, E. M. King, Z. Zhang, T. M. Paul, J. A. Shariq, S. M. Zaharias, J. Zhang

The paper uses RS-mimic peptides to study phase separation of SRSF1, revealing that combined stacking and electrostatic interactions drive this process.

bioRxiv · Oct 24, 2022Biochemistry

Uncovering the mechanism for aggregation in repeat expanded RNA reveals a reentrant transition

O. Kimchi, E. M. King, M. P. Brenner

This study develops a framework to predict RNA repeat aggregation by analyzing bonding and entropy, revealing reentrant transitions and sequence-dependent behavior.

bioRxiv · May 12, 2022Biophysics

Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice

B. Hamza, A. B. Miller, L. Meier, M. Stockslager, E. M. King, S. R. Ng, K. L. DeGouveia, N. Mulugeta, N. L. Calistri, H. Strouf, L. Lin, C. R. Chin, R. Weinberg, A. K. Shalek, T. Jacks, S. Manalis

This study measures CTC kinetics and metastatic potential by exchanging blood between tumor-bearing and healthy mice, finding short CTC half-life and high shedding rates.

bioRxiv · Nov 1, 2020Cancer Biology