Cancer BiologybioRxiv
Highly differentiated CD4 T cells Unequivocally Identify Primary Resistance and Risk of Hyperprogression to PD-L1/PD-1 Immune Checkpoint Blockade in Lung Cancer
M. Zuazo-Ibarra, H. Arasanz, G. Fernandez-Hinojal…·D. Escors
The paper identifies baseline circulating highly-differentiated CD4 T cells as predictors of response or hyperprogression to PD-L1/PD-1 blockade therapy in lung cancer patients.
DOI 10.3390/cancers12020344