Biosynthetic proteins targeting the SARS-CoV-2 spike as anti-virals
S. Thebault, N. Lejal, A. Dogliani, A. Donchet, A. Urvoas, M. Valerio-Lepiniec, M. Lavie, C. Baronti, F. Touret, B. da Costa, C. Bourgon, A. Fraysse, A. Saint-Albin-Deliot, J. Morel, B. Klonjkowski, , B. Delmas
This paper identifies biosynthetic proteins (Reps) that bind the SARS-CoV-2 spike RBD and neutralize the virus, including variants, with high potency and stability.
bioRxiv · May 10, 2022Microbiology