Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells
E. Cecon, A. Oishi, M. Luka, D. Ndiaye-Lobry, A. Francois, M. Lescuyer, F. Panayi, J. Dam, P. Machado, R. Jockers
This paper develops tau biosensors using Nanoluciferase technology to monitor tau conformational changes and seeding activity in living cells, identifying potential therapeutic targets for tauopathies.
bioRxiv · Mar 18, 2022Cell Biology