Structure of human CST-pol-α/primase bound to a telomeric overhang poised for initiation of telomere C-strand synthesis
Q. He, X. Lin, B. L. Chavez, B. L. Lusk, C. J. Lim
The paper reports the structure of the human telomere C-strand fill-in preinitiation complex, revealing how CST and pol-/primase coordinate DNA synthesis.
bioRxiv · Dec 16, 2021Biochemistry