Author

B. L. Neel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:simulation· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

M. Sotomayor· 3 shared R. Araya-Secchi· 3 shared C. R. Nisler· 2 shared S. Walujkar· 2 shared C. Chen· 1 shared C. F. Klanseck· 1 shared D. Choudhary· 1 shared E. Tamilselvan· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiophysics

M. Sotomayor

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Author profile →

3 papers

Recent·Most cited

Collective Mechanical Responses of Cadherin-Based Adhesive Junctions as Predicted by Simulations

B. L. Neel, C. R. Nisler, S. Walujkar, R. Araya-Secchi, M. Sotomayor

This paper uses simulations to study the mechanical responses of different cadherin-based junctions, finding distinct behaviors in adherens junctions and clustered protocadherin junctions under force.

bioRxiv · Jul 29, 2021Biophysics

Elastic versus Brittle Mechanical Responses Predicted for Dimeric Cadherin Complexes

B. L. Neel, C. R. Nisler, S. Walujkar, R. Araya-Secchi, M. Sotomayor

This paper uses molecular dynamics simulations to compare the mechanical responses of classical and clustered cadherin dimers, finding classical cadherins exhibit a two-phased elastic response while clustered protocadherins are brittle and stiffer.

bioRxiv · Jul 29, 2021Biophysics

Structural determinants of protocadherin-15 elasticity and function in inner-ear mechanotransduction

D. Choudhary, Y. Narui, B. L. Neel, L. N. Wimalasena, C. F. Klanseck, P. De-la-Torre, C. Chen, R. Araya-Secchi, E. Tamilselvan, M. Sotomayor

This study reports the structure of PCDH15 and its interactions with CDH23, revealing how its ectodomain functions as a gating spring in inner-ear mechanotransduction.

bioRxiv · Jul 8, 2019 · PreprintBiophysics