Author

B. L. Spencer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Organism:bacteria (other)· 1 Assay:proteomics· 1

Frequent Co-Authors

K. S. Doran· 4 shared P. E. Nagao· 3 shared J. C. Mendonca· 2 shared A. Chatterjee· 1 shared A. H. Nobbs· 1 shared A. M. Job· 1 shared B. A. Duerkop· 1 shared C. M. Robertson· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersMicrobiology

K. S. Doran

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4 papers

Recent·Most cited

Heterogeneity of the group B streptococcal type VII secretion system and influence on colonization of the female genital tract

B. L. Spencer, A. M. Job, C. M. Robertson, Z. A. Hameed, C. Serchejian, C. S. Wiafe-Kwakye, J. C. Mendonca, M. A. Apolonio, P. E. Nagao, M. N. Neely, N. Korotkova, K. V. Korotkov, K. A. Patras, K. S. Doran

This study characterizes the heterogeneity of the T7SS in GBS and shows subtype-specific effects on host colonization and gene expression.

Molecular Microbiology · Jun 26, 2023Peer-reviewedMicrobiology

A type VII secretion system in Group B Streptococcus mediates cytotoxicity and virulence

B. L. Spencer, U. Tak, J. C. Mendonca, P. E. Nagao, M. Niederweis, K. S. Doran

This study identifies a type VII secretion system in Group B Streptococcus that contributes to virulence and cytotoxicity through the WXG100 effector EsxA.

bioRxiv · Jun 15, 2021Microbiology

Genome-wide mutagenesis identifies factors involved in Enterococcus faecalis vaginal adherence and persistence

N. Alhajjar, A. Chatterjee, B. L. Spencer, L. R. Burcham, J. L. E. Willett, G. M. Dunny, B. A. Duerkop, K. S. Doran

This study identifies bacterial factors important for Enterococcus faecalis vaginal colonization and persistence using a transposon mutagenesis screen in a mouse model.

Infection and Immunity · Sep 18, 2020Peer-reviewedMicrobiology

The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis

L. Deng, B. L. Spencer, J. A. Holmes, R. Mu, S. Rego, T. A. Weston, Y. Hu, G. F. Sanches, S. Yoon, N. Park, P. E. Nagao, H. F. Jenkinson, J. A. Thornton, K. S. Seun, A. H. Nobbs, K. S. Doran

bioRxiv · May 10, 2019Microbiology