Interruption of the Intratumor CD8:Treg Crosstalk Improves the Efficacy of PD-1 Immunotherapy
S. N. Geels, A. Moshensky, R. S. Sousa, B. L. Walker, R. Singh, G. Gutierrez, M. Hwang, T. R. Mempel, Q. Nie, S. Othy, F. Marangoni
This study shows that interrupting CD8:Treg crosstalk during PD-1 immunotherapy improves melanoma control by reducing Treg accumulation.
bioRxiv · May 15, 2023 · PreprintImmunology